How do weight-loss drugs like Mounjaro and Wegovy work – and could they help you?
Obesity is a growing health concern in India: national surveys and analyses show a clear rise in overweight and obesity across adults and children over recent years. Many people who struggle to lose weight despite exercise and diet changes are now asking about medical options – including weekly injectable medications such as Mounjaro (tirzepatide) and Wegovy (semaglutide). If you are in Gurgaon and exercise hasn’t worked as expected, understanding how these medicines act, who they help, and what to expect can help you choose the right path.
What these drugs do – the biology in plain language
Both Mounjaro and Wegovy are injectable drugs derived from hormones your gut releases after food. They influence appetite, satiety (the feeling of being full), and how your body handles glucose and stored fat.
- Wegovy (semaglutide) is a GLP-1 receptor agonist. It mimics glucagon-like peptide-1 (GLP-1), a hormone that slows gastric emptying, reduces appetite, and raises feelings of fullness – which together reduce calorie intake and promote weight loss. Large clinical trials have shown meaningful, sustained weight loss with weekly semaglutide.
- Mounjaro (tirzepatide) is a newer, dual agonist: it activates both GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 receptors. By stimulating two complementary gut-hormone pathways, tirzepatide tends to produce larger average weight losses in trials than single-pathway drugs – it reduces appetite, slows digestion, and improves metabolic signals that affect fat storage and blood sugar.
How effective are they?
Clinical trials demonstrate substantial, clinically meaningful weight loss when these medicines are used with lifestyle support (diet and activity):
- Semaglutide (Wegovy) produced average weight losses around ~15% of body weight in pivotal trials versus placebo, with many patients achieving ≥10% weight loss at 68-72 weeks.
- Tirzepatide (Mounjaro) showed even larger reductions in SURMOUNT trials – mean weight losses of ~16% to >22%depending on dose – with a high proportion of participants losing ≥20% in some groups. These are trial averages; individual results vary.
Are these drugs available and used in India?
Yes – both semaglutide (Wegovy) and tirzepatide (Mounjaro / related brands) have been launched or cleared for use in India in recent regulatory steps and commercial introductions, improving access for Indian patients seeking medically supervised weight-loss treatment. Availability and brand names may evolve (local pricing and supply vary), so it’s important to consult an authorised clinic.
Who should consider these injections?
These medications are prescription treatments for adults with:
- Body mass index (BMI) in the obesity range (typically BMI ≥30 kg/m²), or
- BMI ≥27 kg/m² with at least one weight-related medical condition (for example, type 2 diabetes, high blood pressure).
They’re especially considered when lifestyle measures (diet, exercise) alone have not achieved meaningful weight loss and when supervised by a trained physician. Not everyone is a candidate – a medical history review, examination, and baseline tests are required.
Safety, side effects and what to expect
Common side effects are gastrointestinal – nausea, diarrhea, constipation, and abdominal discomfort – usually greatest when doses are being increased and often improve with time. Rare but serious risks (pancreatitis, gallbladder issues, severe allergic reactions) have been reported, so careful monitoring is needed. These medications can also affect absorption of oral drugs due to slower gastric emptying, so tell your doctor all medicines you take. Your physician will explain risks, monitor labs, and adjust treatment as needed.
Practical points for people in Delhi NCR & Gurgaon
- Multidisciplinary approach: Best results come from combining medication with nutrition guidance, physical activity, and behaviour support.
- Medical supervision is essential: Dose escalation, monitoring for side effects, and deciding how long to continue therapy should be done by an experienced clinician.
- Cost & continuity: These are long-term prescription therapies; discuss costs, supply, and follow-up plans before starting.
At Gutwell, we provide Mounjaro and Wegovy injections in Gurgaon under the clinical guidance of Dr. Sukrit Singh Sethi. Our team evaluates your medical history, runs baseline tests, and creates a personalised plan combining medication, diet counselling and activity plans so you get safe and effective care. If you’re struggling with obesity despite exercise, we can assess whether a medically supervised injection therapy is right for you.
Ready to take the next step? Book a consultation at Gutwell with Dr. Sukrit Singh Sethi to discuss Weight Loss Injection in Gurgaon and Wegovy Treatment in Gurgaon tailored to your needs. Call us or book online for a one-to-one assessment and personalised plan.
FAQs
1. How quickly will I lose weight on Mounjaro or Wegovy?
Weight loss varies – many people see steady reductions over months; pivotal trials report major changes by 6-12 months when combined with lifestyle support. Individual results depend on dose, adherence, and background care.
2. Are these drugs safe long term?
Long-term safety data are growing. Ongoing studies and real-world monitoring guide recommendations; your doctor will review risks vs benefits and monitor you regularly.
3. Can I stop the injection after I reach my goal weight?
Stopping usually leads to some degree of weight regain unless lifestyle changes are maintained or another plan is in place. Discuss a long-term strategy with your clinician.
4. Will insurance cover treatment in India?
Coverage varies by insurer and policy. Check your plan and ask Gutwell’s team for support documentation for claims.
5. How do I book at Gutwell?
Contact Gutwell to schedule a consultation with Dr. Sukrit Singh Sethi. We’ll review your suitability, explain expected outcomes, and outline costs and follow up.
Disclaimer:
This content is for informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment; always consult a qualified doctor before starting any weight-loss medication or injection.